Treatment of menopausal symptoms by an extract from the roots of rhapontic rhubarb: the role of estrogen receptors
نویسندگان
چکیده
A dry extract from the roots of rhapontic rhubarb (extract Rheum rhaponticum (L.); ERr) has been commercially available in Germany for over two decades to treat menopausal symptoms. However, the molecular basis of its clinical effectiveness remains obscure. This article reviews the in vitro and in vivo data of its estrogenic actions, particularly those mediated by estrogen receptor-beta (ERbeta).
منابع مشابه
Efficacy of the special extract ERr 731 from rhapontic rhubarb for menopausal complaints: a 6-month open observational study.
BACKGROUND The special extract ERr 731 from the roots of rhapontic rhubarb has been in widespread use in Germany since 1993, and the current regulations have required an evaluation of its risk:benefit ratio in daily use. OBJECTIVE To demonstrate the efficacy and tolerability ofERr 731 in menopausal women in everyday practice. DESIGN Three hundred sixty-three menopausal women with menopausal...
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